Delineation of the centromeric and telomeric chromosome segment 11p15.5 lung cancer suppressor regions LOH11A and LOH11B.

doi:10.1002/(sici)1098-2264(199702)18:2<111::aid-gcc5>3.0.co;2-5

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Article

Delineation of the centromeric and telomeric chromosome segment 11p15.5 lung cancer suppressor regions LOH11A and LOH11B.

Genes, chromosomes & cancer - 1 Feb 1997

O'Briant K C, Bepler G

Abstract excerpt

We have reported frequent allele loss for two separate regions identified by the markers D11S12 and HRAS on chromosome 11p15.5. D11S12 allele loss was associated with tumor stage and type and HRAS allele loss with cigarette consumption, sex, and survival. To positionally clone the putative tumor...

Topics

Alleles
Centromere
Chromosome Deletion
Chromosomes, Human, Pair 11
Heterozygote
Humans
Lung Neoplasms
Telomere

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