Article
Multiple chromosomal aberrations and 11p allelotyping in lung cancer cell lines.
Cancer genetics and cytogenetics - 1 Oct 1995
Bepler G, Koehler A
Abstract excerpt
Cytogenetic and molecular genetic studies have implicated many chromosomal aberrations in the pathogenesis of lung cancer. Deletions on 3p and 9p are presently the primary target for positional cloning of putative tumor suppressor genes. We have recently reported frequent loss of heterozygosity in three separate regions (HRAS, D11S12, D11S16) on 11p in freshly resected lung cancer specimens. Here we report...
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