Article
Smoking, gender, and survival association with allele loss for the LOH11B lung cancer region on chromosome 11.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 1997
Schreiber G, Fong K M, Peterson B, Johnson B E, O'Briant K C, Bepler G
Abstract excerpt
We have reported frequent allele loss for the marker HRAS on chromosome 11p in human lung cancer and defined the smallest common region of deletion (designated LOH11B) to approximately 500 kb. Here, we investigated the association of allele loss for LOH11B with epidemiological, pathological, and clinical parameters. Analysis of allele loss was performed using Southern blotting on a cohort of 200 patients with...
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