Article
Allelic losses in human chromosome 11 in lung cancers.
Genes, chromosomes & cancer - 1 May 1995
Iizuka M, Sugiyama Y, Shiraishi M, Jones C, Sekiya T
Abstract excerpt
The relatively frequent loss of heterozygosity at loci on the short arm of chromosome 11 in human lung cancers has suggested the presence of a putative tumor suppressor gene. For location of the gene, a fine deletion map of human chromosome 11 was constructed by analysis of DNAs from 79 lung cancers with 31 sequence-tagged-site markers that dotted chromosome 11 and detected polymorphic changes in nucleotide...
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