Article
Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas.
Molecular carcinogenesis - 1 Jun 1996
Herzog C R, Chen B, Wang Y, Schut H A, You M
Abstract excerpt
An allelotype analysis of lung tumors in mouse hybrids was conducted to identify common regions of allelic loss. By using 50 informative genetic markers, the autosomes of 36 (A/J x C3H/HeJ) F1 adenocarcinomas were examined. Additional adenocarcinomas from as many as 72 (C3H/HeJ x A/J) F1 and 15 (...
Topics
- Adenocarcinoma
- Alleles
- Animals
- Chromosomes
- Gene Deletion
- Genes, Tumor Suppressor
- Heterozygote
- Lung Neoplasms
- Mice
- Mice, Inbred Strains