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Article

Idiotypic analysis of anti-nucleosome monoclonal antibodies derived from lupus mice.

Journal of autoimmunity - 1 Oct 1997

Brard F, Gilbert D, Jovelin F, Tron F

Abstract excerpt

3F6 and 2E1 are anti-(H2A-H2B) monoclonal antibodies derived from a 12-month-old (NZBxNZW)F1 mouse that diverged from the same clonal precursor by somatic mutations. Rabbit anti-idiotypic antisera were prepared against these two monoclonal antibodies and used as probes to analyse the properties and expression of 3F6 and 2E1 idiotypes. Both idiotypes were conformational, distant from the antigen binding site and...

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Identifiers

PMID: 9376069
DOI: 10.1006/jaut.1997.9999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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