Article
Serological analysis of H-2 mutations using monoclonal antibodies.
Journal of immunogenetics - 1 Jan 2000
Bluestone J A, McKenzie I F, Melvold R W, Ozato K, Sandrin M S, Sharrow S O, Sachs D H
Abstract excerpt
Nine H-2Kb and H-2Db mutants were examined for serological differences from the wild type C57BL/6 using a panel of monoclonal antibodies (mAbs). Several differences (between the Kb mutants) were established with these mAbs. The bm3 and bm11 mutants could be distinguished serologically even though they have very similar amino acid changes. Conversely, the bm 1 and bm 10 mice, which differ in their sites of Kb...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Epitopes
- H-2 Antigens
- Mice
- Mice, Inbred Strains
- Mutation