Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype.

The Journal of experimental medicine - 1 Dec 1991

Manheimer-Lory A, Katz J B, Pillinger M, Ghossein C, Smith A, Diamond B

Abstract excerpt

Anti-double-stranded DNA antibodies are the hallmark of the disease systemic lupus erythematosus and are believed to contribute to pathogenesis. While a large number of anti-DNA antibodies from mice with lupus-like syndromes have been characterized and their variable region genes sequenced, few human anti-DNA antibodies have been reported. We describe here the variable region gene sequences of eight antibodies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Molecular Sequence Data

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 1660528
DOI: 10.1084/jem.174.6.1639
PMCID: PMC2119023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype.PMID 1660528Read ↗

Characterization of two human anti-DNA antibodies bearing the pathogenic idiotype 8.12.Semantic proximity Read ↗

The structure of human lupus anti-DNA antibodies.Semantic proximity Read ↗

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus.Semantic proximity Read ↗

The human antibody repertoire to infectious agents: implications for disease pathogenesis.Semantic proximity Read ↗

Affinity maturation generates pathogenic antibodies with dual reactivity to DNase1L3 and dsDNA in systemic lupus erythematosusSemantic proximity Read ↗

Anti-DNA antibodies: aspects of structure and pathogenicity.Semantic proximity Read ↗

Dissecting human antibody responses: useful, basic and surprising findings.Semantic proximity Read ↗

The evolution of human anti-double-stranded DNA autoantibodies.Semantic proximity Read ↗

Neutralizing anti-DNase1L3 antibodies derive from autoreactive VH4-34<sup>+</sup>-B cells and associate with the interferon signature in SLESemantic proximity Read ↗

Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunitySemantic proximity Read ↗

Lupus-specific antibodies reveal an altered pattern of somatic mutation.Semantic proximity Read ↗

Antibodies to DNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.