Article
Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype.
The Journal of experimental medicine - 1 Dec 1991
Manheimer-Lory A, Katz J B, Pillinger M, Ghossein C, Smith A, Diamond B
Abstract excerpt
Anti-double-stranded DNA antibodies are the hallmark of the disease systemic lupus erythematosus and are believed to contribute to pathogenesis. While a large number of anti-DNA antibodies from mice with lupus-like syndromes have been characterized and their variable region genes sequenced, few h...
Topics
- Amino Acid Sequence
- Antibodies, Antinuclear
- Base Sequence
- Cell Line, Transformed
- Genes, Immunoglobulin
- Herpesvirus 4, Human
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Idiotypes
- Immunoglobulin Variable Region
- Molecular Sequence Data
