Article
No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample.
Neuroscience letters - 19 Sept 1997
Fallin D, Kundtz A, Town T, Gauntlett A C, Duara R, Barker W, Crawford F, Mullan M
Abstract excerpt
It is now commonly known that possession of the epsilon4 allele of the apolipoprotein E (APOE) gene confers an increased risk for both familial and sporadic Alzheimer's disease (AD), in a dose-dependent way. Other genes that may play a role in AD, either through independent association with the d...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Case-Control Studies
- Chi-Square Distribution
- Community Medicine
- Female
- Genetic Testing
- Genotype
- Humans