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Article

Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease.

Neuroscience letters - 9 Aug 2002

Martin-Rehrmann Matthew D, Cho Hyun Soon, Rebeck G William

Abstract excerpt

A recent genetic study demonstrated associations between an altered risk of Alzheimer's disease (AD) and two polymorphisms in the lipoprotein lipase (LPL) gene, Asn291Ser and Ser447Ter. LPL immunostains senile plaques, and is a ligand of the low-density lipoprotein receptor-related protein (LRP), a major apolipoprotein E (apoE) receptor. LPL increases the cellular uptake of apoE via LRP, and polymorphisms in LPL...

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Source

Identifiers

PMID: 12133567
DOI: 10.1016/s0304-3940(02)00511-6

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease.PMID 12133567Read ↗

Lipoprotein lipase mutations and Alzheimer's disease.Semantic proximity Read ↗

Roles for lipoprotein lipase in Alzheimer's disease: an association study.Semantic proximity Read ↗

No association between the lipoprotein lipase S447X polymorphism and Alzheimer's disease.Semantic proximity Read ↗

Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.Semantic proximity Read ↗

Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease.Semantic proximity Read ↗

No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample.Semantic proximity Read ↗

No association between low density lipoprotein receptor genetic variants and Alzheimer's disease risk.Semantic proximity Read ↗

Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease.Semantic proximity Read ↗

No association of lipase C polymorphisms with Alzheimer's disease.Semantic proximity Read ↗

A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology.Semantic proximity Read ↗

Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.Semantic proximity Read ↗

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.Semantic proximity Read ↗

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