Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease.

Neuroscience letters - 15 Jul 2005

Pritchard Antonia, Harris Judith, Pritchard Colin W, St Clair David, Lemmon Helen, Lambert Jean-Charles, Chartier-Harlin Marie-Christine, Hayes Angela, Thaker Uma, Iwatsubo Takeshi, Mann David M A, Lendon Corinne

Abstract excerpt

Genome scans in sporadic Alzheimer's disease (AD) have revealed a possible susceptibility locus on chromosome 12. The low density lipoprotein receptor related protein (LRP1) gene lies within this area of linkage. Eighteen previous AD case-control studies have investigated the C766T polymorphism in LRP1 with conflicting results, including a protective effect on AD of the T allele, an increased susceptibility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amyloid beta-Peptides

Share to Apolipoproteins E

Share to Immunohistochemistry

Share to Low Density Lipoprotein Receptor-Related Protein-1

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 15925094
DOI: 10.1016/j.neulet.2005.03.016

Genes

LRP1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease.PMID 15925094Read ↗

Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.Semantic proximity Read ↗

No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample.Semantic proximity Read ↗

Regional European differences in allele and genotype frequencies of low density lipoprotein receptor-related protein 1 polymorphism in Alzheimer's disease.Semantic proximity Read ↗

Lack of interaction between LRP1 and A2M polymorphisms for the risk of Alzheimer disease.Semantic proximity Read ↗

The LDLR locus in Alzheimer's disease: a family-based study and meta-analysis of case-control data.Semantic proximity Read ↗

No association between low density lipoprotein receptor genetic variants and Alzheimer's disease risk.Semantic proximity Read ↗

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.Semantic proximity Read ↗

Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease.Semantic proximity Read ↗

Candidate Gene Association Studies in Sporadic Alzheimer’s DiseaseSemantic proximity Read ↗

Meta-analysis of the association between the interleukin-1A -889C/T polymorphism and Alzheimer's disease.Semantic proximity Read ↗

[Meta-analysis of the association of the LRP C766T polymorphism with the risk of Alzheimer's disease].Semantic proximity Read ↗

Case-control study and meta-analysis of low density lipoprotein receptor-related protein gene exon 3 polymorphism in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.