Article
No association between the very low density lipoprotein receptor gene and late-onset Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and clinic samples.
Genetic epidemiology - 1 Jan 1997
Fallin D, Gauntlett A C, Scibelli P, Cai X, Duara R, Gold M, Crawford F, Mullan M
Abstract excerpt
It is now commonly known that possession of one of the three common alleles of the apolipoprotein E (APOE) gene (allele epsilon 4) confers an increased risk for both familial and sporadic Alzheimer's disease (AD), and that this risk is dose-dependent. Other genes that may play a role in AD, eithe...
Topics
- Age of Onset
- Aged
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Female
- Gene Frequency
- Genotype
- Humans
- Logistic Models
- Male
- Middle Aged
- Polymorphism, Genetic
- Receptors, LDL
- Risk Factors