Article
Tumor necrosis factor locus polymorphisms in rheumatoid arthritis.
Tissue antigens - 1 Sept 1997
Field M, Gallagher G, Eskdale J, McGarry F, Richards S D, Munro R, Oh H H, Campbell C
Abstract excerpt
We examined six polymorphic elements in the tumor necrosis factor (TNF) locus and determined their allelic distribution in 98 Caucasian rheumatoid arthritis patients in comparison with 91 ethnically-matched controls. Polymorphic elements at four biallelic sites were distributed similarly between patients and controls, irrespective of the presence or absence of DR4. Differences were observed between the two groups...
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