Article
Primary association of tumor necrosis factor-region genetic markers with susceptibility to rheumatoid arthritis.
Arthritis and rheumatism - 1 Jun 2000
Martínez A, Fernández-Arquero M, Pascual-Salcedo D, Conejero L, Alves H, Balsa A, de la Concha E G
Abstract excerpt
OBJECTIVE: To determine whether tumor necrosis factor (TNF) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) independently of the HLA-DR shared epitope. METHODS: Fifty-two Spanish families with one or more affected members were typed for HLA-DRB1, TNF promoter polymor...
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