Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor alpha promoter polymorphisms in patients with juvenile idiopathic arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Schmeling H, Wagner U, Peterson A, Horneff G

Abstract excerpt

OBJECTIVE: To investigate the potential association of tumor necrosis factor-alpha (TNF) promoter alleles within subtypes of juvenile idiopathic arthritis (JIA) compared to healthy controls in a Caucasian population. METHODS: TNF-alpha promoter polymorphisms at positions -163, -238, -244, -308, -376 were determined in 228 patients with JIA and 196 healthy individuals. Genomic DNA was isolated and a PCR fragment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Juvenile
Share to Arthritis, Psoriatic
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Sequence Analysis, DNA

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 16539828

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor alpha promoter polymorphisms in patients with juvenile idiopathic arthritis.PMID 16539828Read ↗

Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis.Semantic proximity Read ↗

TNF-α gene polymorphisms and juvenile idiopathic arthritis: Influence on disease outcome and therapeutic response.Semantic proximity Read ↗

TNF-alpha promoter gene polymorphisms in Spanish children with persistent oligoarticular and systemic-onset juvenile idiopathic arthritis.Semantic proximity Read ↗

Tumour necrosis factor alpha promoter polymorphisms and etanercept therapy in juvenile idiopathic arthritis.Semantic proximity Read ↗

Tumour necrosis factor alpha G-->A -238 and G-->A -308 polymorphisms in juvenile idiopathic arthritis.Semantic proximity Read ↗

Association of tumour necrosis factor-alpha G/A -238 and G/A -308 single nucleotide polymorphisms with juvenile idiopathic arthritis.Semantic proximity Read ↗

Tumor necrosis factor-α -308 A/G gene polymorphism in children with juvenile idiopathic arthritis: relation to disease activity, damage, and functional status.Semantic proximity Read ↗

TNF promoter -308 A/G and -238 A/G polymorphisms and juvenile idiopathic arthritis: a meta-analysis.Semantic proximity Read ↗

Tumor necrosis factor-alpha single nucleotide polymorphisms in juvenile systemic lupus erythematosus.Semantic proximity Read ↗

308G/A and 238G/A polymorphisms in the TNF-α gene may not contribute to the risk of arthritis among Turkish psoriatic patientsSemantic proximity Read ↗

TNF gene promoter region polymorphisms and association with young-onset rheumatoid arthritis.Semantic proximity Read ↗

TNF-α gene polymorphisms: association with disease susceptibility and response to anti-TNF-α treatment in psoriatic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.