Article
Different gene loci within the HLA-DR and TNF regions are independently associated with susceptibility and severity in Spanish rheumatoid arthritis patients.
Tissue antigens - 1 Apr 2000
Hajeer A H, Dababneh A, Makki R F, Thomson W, Poulton K, González-Gay M A, García-Porrúa C, Mattey D L, Ollier W E
Abstract excerpt
The aim of this study was to investigate whether polymorphisms in the tumor necrosis factor (TNF) and HLA-DRB1 gene regions are independently associated with rheumatoid arthritis (RA) in a population from Lugo region of northwestern Spain. RA patients (n=179) attending hospital outpatient clinics in Lugo, northwestern Spain and matched controls (n=145) were recruited. RA susceptibility in this population was...
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