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Article

Genetic variants that predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis: current challenges and future directions

1 Mar 2008

Abstract excerpt

PURPOSE OF REVIEW: Tumor necrosis factor alpha (TNF) inhibitors are a mainstay of treatment in rheumatoid arthritis, yet there are no effective clinical or biomarker predictors of which patients will respond. Here we review genetic association studies conducted to search for DNA biomarkers of response to anti-TNF therapy. RECENT FINDINGS: The entirety of genetic association studies to date that focus on response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18349743
DOI: 10.1097/bor.0b013e3282f5135b

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