Article
Pharmacogenetics: Anti-TNF therapy in RA--towards personalized medicine?
Nature reviews. Rheumatology - 1 Mar 2011
Verweij Cornelis L
Abstract excerpt
A substantial proportion of patients with rheumatoid arthritis do not respond to tumor necrosis factor blocking therapy. Results of a large genome-wide association study demonstrate evidence of novel genetic factors that determine response to treatment, which could provide a basis for individualizing therapy.
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