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Article

TNF +489 polymorphism does not contribute to susceptibility to rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Low A S, Gonzalez-Gay M A, Akil M, Amos R S, Bax D E, Cannings C, Hajeer A, Till S H, Winfield J, Ollier W E, Wilson A G

Abstract excerpt

OBJECTIVES: To determine if a tumour necrosis factor (TNF +489) polymorphism is associated with susceptibility to rheumatoid arthritis (RA). METHODS: Two European populations were studied: 217 controls and 238 patients from the north of England and 145 controls and 179 patients from Spain. HLA-DRB1 and TNF +489 markers were typed using polymerase chain reaction based methods. RESULTS: Strong associations were...

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PMID: 12508775

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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