Article
Validation of HLA-DR locus typing in forensic specimens by combining PCR-SSP with PCR-RFLP.
Journal of forensic sciences - 1 Sept 1997
Ota M, Katsuyama Y, Liu C Y, Arakura A, Fukushima H
Abstract excerpt
The applicability of HLA-DR DNA typing combined with PCR-SSP (sequence specific primers) and PCR-RFLP (restriction fragment length polymorphism) to forensic practice was investigated. PCR-SSP was as effective as serological HLA-DR typing in determining DR types. For more precise definition of DRB1 alleles encoding DR2, DR4, and DR8 antigens, which are fairly common in Japan, we used the PCR-RFLP method. For...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.