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Article

A new HLA-DRB1 genotyping method using single nucleotide polymorphism (SNP) analysis with multiplex primer extension reactions and its application to mixed samples.

Acta medica Okayama - 1 Oct 2005

Imabayashi Kiyomi, Yamamoto Yuji, Inagaki Sachiyo, Doi Yusuke, Yositome Kei, Miyaishi Satoru, Ishizu Hideo

Abstract excerpt

We have improved on conventional methods for HLA-DRB1 genotyping and devised a new method that is simple, cost-effective, and adequately applicable to routine forensic practice. This method consists of group-specific polymerase chain reaction (PCR) of the exon 2 region of the HLA-DRB1 gene and simultaneous detection of single nucleotide polymorphisms (SNPs) at multiple sites using multiplex primer extension...

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PMID: 16286957
DOI: 10.18926/AMO/31971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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