Article
Mutational analysis of the BRCA1 tumor suppressor gene in endometrial carcinoma.
Gynecologic oncology - 1 Sept 1997
Liu F S, Ho E S, Shih R T, Shih A
Abstract excerpt
OBJECTIVE: To investigate whether alteration of BRCA1 tumor suppressor gene occurs in sporadic endometrial carcinomas. METHODS: Genomic DNAs were prepared from 33 consecutively collected endometrial carcinoma tissues for BRCA1 mutational analysis. To screen for BRCA1 mutation, polymerase chain reaction (PCR) amplification and single strand conformation polymorphism (SSCP) technique were used with 41 overlapping...
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