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Article

Evaluation of germline PTEN mutations in endometrial cancer patients.

Gynecologic oncology - 1 Jan 2005

Black Destin, Bogomolniy Faina, Robson Mark E, Offit Kenneth, Barakat Richard R, Boyd Jeff

Abstract excerpt

BACKGROUND AND OBJECTIVE: Cowden Syndrome is a rare autosomal dominant disorder characterized by multiple hamartomas, increased risks of breast and thyroid cancers, and possibly endometrial carcinoma. Susceptibility to Cowden syndrome is conferred by germline mutation of the PTEN tumor suppressor gene, and somatic mutations of PTEN are common in sporadic endometrial carcinomas. The aim of this study was to test...

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Share to Tumor Suppressor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphoric Monoester Hydrolases

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 15589575
DOI: 10.1016/j.ygyno.2004.09.024

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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