Article
Risk of endometrial carcinoma associated with BRCA mutation.
Gynecologic oncology - 1 Mar 2001
Levine D A, Lin O, Barakat R R, Robson M E, McDermott D, Cohen L, Satagopan J, Offit K, Boyd J
Abstract excerpt
OBJECTIVE: Inherited mutations in the BRCA1 or BRCA2 genes are associated with a greatly increased lifetime risk of breast and ovarian cancers and a modestly increased risk of several other cancer types. Several case reports of endometrial carcinoma in women with a BRCA mutation have led to speculation regarding the effect of these genes on the risk of endometrial cancer. The purpose of this study was to test the...
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