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Article

Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines.

Molecular carcinogenesis - 1 Aug 1996

Terry L A, Boyd J, Alcorta D, Lyon T, Solomon G, Hannon G, Berchuck A, Beach D, Barrett J C

Abstract excerpt

p21/WAF1/CIP1/SDI1 is an important cell-cycle mediator with tumor suppressor gene capabilities, and its inactivation could potentially lead to tumor progression. Because tumor suppressor genes are commonly inactivated by somatic and germline mutations, we analyzed a variety of human tumor cell lines for p21 mutations. We used single-strand conformational analysis and direct sequencing to identify possible...

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Source

Identifiers

PMID: 8784465
DOI: 10.1002/(SICI)1098-2744(199608)16:4<221::AID-MC6>3.0.CO;2-I

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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