Article
Microsatellite instability in sporadic endometrial carcinoma.
Journal of the National Cancer Institute - 17 Aug 1994
Duggan B D, Felix J C, Muderspach L I, Tourgeman D, Zheng J, Shibata D
Abstract excerpt
BACKGROUND: Recent studies have demonstrated ubiquitous somatic microsatellite mutations in some cancers of the colon, endometrium, stomach, and pancreas. PURPOSE: Our purpose was to characterize the frequency and nature of this replication error (RER) or mutator phenotype in sporadic endometrial...
Topics
- Adult
- Autoradiography
- Carcinoma
- DNA Replication
- DNA, Neoplasm
- DNA, Satellite
- Endometrial Neoplasms
- Female
- Genes, ras
- Humans
- Middle Aged
- Mutation
- Phenotype