Linkage analysis under locus heterogeneity: behaviour of the A-test in complex analyses.

doi:10.1159/000154416

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Article

Linkage analysis under locus heterogeneity: behaviour of the A-test in complex analyses.

Human heredity - 1 Jan 2000

Janssen B, Halley D, Sandkuijl L

Abstract excerpt

The admixture test (A-test) is a popular method for the analysis of linkage data when locus heterogeneity is suspected. It can be applied on pairwise linkage data, multipoint data and even for the simultaneous analysis of data from multiple dispersed candidate regions. However, very little is kno...

Topics

Bias
Female
Genetic Heterogeneity
Genetic Linkage
Humans
Male
Models, Statistical
Pedigree
Phenotype

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