Article
Heterogeneity for multiple disease loci in linkage analysis.
Human heredity - 1 Jul 1999
Bhat A, Heath S C, Ott J
Abstract excerpt
Many mendelian traits show heterogeneity; that is, the disease phenotype in different families may be caused by genes at different locations. In linkage analysis, this admixture type of heterogeneity (locus heterogeneity) has often been accommodated with one of the HOMOG programs, which thus far have been restricted to at most two disease gene locations. Here, an extension to an arbitrary number of disease...
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