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Article

Power to detect linkage with heterogeneity in samples of small nuclear families.

American journal of medical genetics - 15 Jul 1993

Levinson D F

Abstract excerpt

Computer simulation methods were used to investigate the power of genetically homogeneous or heterogeneous samples of nuclear families to detect linkage of a rare dominant disease allele to flanking DNA markers (three-point analysis, admixture text). Phase was assumed to be unknown (no grandparents available), and unaffected siblings were not considered. A sample of 95 families with an ill parent and two ill...

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Identifiers

PMID: 8362931
DOI: 10.1002/ajmg.1320480208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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