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Article

Detecting linkage disequilibrium in the presence of locus heterogeneity.

Annals of human genetics - 1 May 2006

Wang D, Huang J

Abstract excerpt

Locus heterogeneity is a common phenomenon in complex diseases and is one of the most important factors that affect the power of either linkage or linkage disequilibrium (LD) analysis. In linkage analysis, the heterogeneity LOD score (HLOD) rather than LOD itself is often used. However, the existing methods for detecting linkage disequilibrium, such as the TDT and many of its variants, do not take into account...

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Identifiers

PMID: 16674561
DOI: 10.1111/j.1529-8817.2005.00229.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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