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Article

Counselling under genetic heterogeneity: a practical approach.

Clinical genetics - 1 Feb 1991

Narod S

Abstract excerpt

Hereditary diseases due to mutation at different gene loci may be indistinguishable phenotypically. In these situations genetic risk predictions using polymorphic markers may be hampered if an individual family is not sufficiently informative to permit it to be assigned to one or the other linkage group. To provide the most usefull estimates of risk, the probability of linkage to a particular chromosome region...

Topics

Genetic Counseling
Genetic Diseases, Inborn
Genetic Linkage
Genetic Markers
Genetic Testing
Humans
Osteogenesis Imperfecta
Pedigree
Phenotype
Polycystic Kidney Diseases
Predictive Value of Tests
Recurrence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2015693
DOI: 10.1111/j.1399-0004.1991.tb02998.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2015693-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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