Article
Counselling under genetic heterogeneity: a practical approach.
Clinical genetics - 1 Feb 1991
Narod S
Abstract excerpt
Hereditary diseases due to mutation at different gene loci may be indistinguishable phenotypically. In these situations genetic risk predictions using polymorphic markers may be hampered if an individual family is not sufficiently informative to permit it to be assigned to one or the other linkage group. To provide the most usefull estimates of risk, the probability of linkage to a particular chromosome region...
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