Article
Combination of linkage evidence in complex inheritance.
Human heredity - 1 Jan 2001
Zhang W, Collins A, Morton N E
Abstract excerpt
The central problem of complex inheritance is to combine evidence from data that typically differ in markers, phenotypes, ascertainment, and other factors, without sacrificing the reliability that lods have given to linkage mapping for major loci. Here we evaluate 5 possible solutions on 200 replicates simulated in Genetic Analysis Workshop 10. Two methods differ from less efficient ones by distinguishing the...
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