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Article

Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation.

Cell - 11 Jul 1997

Saitoh S, Takahashi K, Yanagida M

Abstract excerpt

Disorder in sister chromatid separation can lead to genome instability and cancer. A temperature-sensitive S. pombe mis6-302 frequently loses a minichromosome at 26 degrees C and abolishes equal segregation of regular chromosomes at 36 degrees C. The mis6+ gene is essential for viability, and its deletion results in missegregation identical to mis6-302. Mis6 acts before or at the onset of S phase, and mitotic...

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Source

Identifiers

PMID: 9230309
DOI: 10.1016/s0092-8674(00)80320-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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