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Article

Different domains of Sgs1 are required for mitotic and meiotic functions.

Genes & genetic systems - 1 Dec 2000

Miyajima A, Seki M, Onoda F, Ui A, Satoh Y, Ohno Y, Enomoto T

Abstract excerpt

The SGS1 of Saccharomyces cerevisiae is a homologue for human Bloom's syndrome, Werner's syndrome, and Rothmund-Thomson's syndrome causative genes. Disruptants of SGS1 show high sensitivity to methyl methanesulfonate (MMS) and hydroxyurea, and hyper recombination phenotypes including interchromosomal homologous recombination in mitotic growth. In addition, sgs1 disruptants show poor sporulation and a reduced...

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Identifiers

PMID: 11280006
DOI: 10.1266/ggs.75.319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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