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Article

csi2p modulates microtubule dynamics and organizes the bipolar spindle for chromosome segregation.

Molecular biology of the cell - 1 Dec 2014

Costa Judite, Fu Chuanhai, Khare V Mohini, Tran Phong T

Abstract excerpt

Proper chromosome segregation is of paramount importance for proper genetic inheritance. Defects in chromosome segregation can lead to aneuploidy, which is a hallmark of cancer cells. Eukaryotic chromosome segregation is accomplished by the bipolar spindle. Additional mechanisms, such as the spindle assembly checkpoint and centromere positioning, further help to ensure complete segregation fidelity. Here we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25253718
DOI: 10.1091/mbc.E14-09-1370
PMCID: PMC4244199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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