Article
Regulation of active genome integrity and expression by Rad26p.
Nucleus (Austin, Tex.) - 1 Jan 2014
Malik Shivani, Bhaumik Sukesh R
Abstract excerpt
Rad26p is a SWI/SNF-like ATPase in yeast, and is conserved among eukaryotes. Both Rad26p and its human homolog CSB (Cockayne syndrome group B) are involved in regulation of chromatin structure, transcription and DNA repair. Thus, mutations or malfunctions of these proteins have significant effects on cellular functions. Mutations in CSB are associated with Cockayne syndrome (CS) that is characterized by...
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