Article
The chromodomain protein Swi6: a key component at fission yeast centromeres.
Science (New York, N.Y.) - 8 Sept 1995
Ekwall K, Javerzat J P, Lorentz A, Schmidt H, Cranston G, Allshire R
Abstract excerpt
Centromeres attach chromosomes to the spindle during mitosis, thereby ensuring the equal distribution of chromosomes into daughter cells. Transcriptionally silent heterochromatin of unknown function is associated with centromeres in many organisms. In the fission yeast Schizosaccharomyces pombe, the silent mating-type loci, centromeres, and telomeres are assembled into silent heterochromatin-like domains. The...
Topics
- Centromere
- Chromosomes, Fungal
- Fluorescent Antibody Technique
- Fungal Proteins
- Genes, Fungal
- Genes, Mating Type, Fungal
- Heterochromatin
- In Situ Hybridization, Fluorescence
- Interphase
- Mitosis
- Mutation