Article
Temperature-dependent modulation of chromosome segregation in msh4 mutants of budding yeast.
PloS one - 9 Oct 2009
Chan Andrew Chi-Ho, Borts Rhona H, Hoffmann Eva
Abstract excerpt
BACKGROUND: In many organisms, homologous chromosomes rely upon recombination-mediated linkages, termed crossovers, to promote their accurate segregation at meiosis I. In budding yeast, the evolutionarily conserved mismatch-repair paralogues, Msh4 and Msh5, promote crossover formation in conjunction with several other proteins, collectively termed the Synapsis Initiation Complex (SIC) proteins or 'ZMM's...
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