Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitivity of transformed fibroblasts for intercellular induction of apoptosis is determined by their transformed phenotype.

Experimental cell research - 10 Jul 1997

Beck E, Schäfer R, Bauer G

Abstract excerpt

Intercellular induction of apoptosis defines a potential control mechanism of oncogenesis. It is based on induction of apoptosis in transformed fibroblasts by neighboring nontransformed fibroblasts. Transforming growth factor type beta (TGF-beta) represents the initial triggering molecule to indu...

Topics

Animals
Apoptosis
Blood Platelets
Cell Line, Transformed
Chromatin
Fibroblasts
Humans
Mice
Mice, Inbred C3H
Oncogene Protein pp60(v-src)
Phenotype
Rats
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transformation, Genetic

Transforming Growth Factor beta

Source

Identifiers

PMID: 9223369
DOI: 10.1006/excr.1997.3587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9223369-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitivity of transformed fibroblasts for intercellular induction of apoptosis is determined by their transformed phenotype.PMID 9223369Read ↗

Intercellular induction of apoptosis through modulation of endogenous survival factor concentration: a review.Semantic proximity Read ↗

Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant.Semantic proximity Read ↗

Direct transforming activity of TGF-beta on rat fibroblasts.Semantic proximity Read ↗

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.Semantic proximity Read ↗

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts.Semantic proximity Read ↗

A dominant negative Raf-1 mutant prevents v-Src-induced transformation.Semantic proximity Read ↗

Novel revertants of H-ras oncogene-transformed R6-PKC3 cells.Semantic proximity Read ↗

Reversion by deletion of transforming oncogene following interferon-beta and retinoic acid treatment.Semantic proximity Read ↗

Cell transforming genes and tumor progression: in vivo unified secondary phenotypic cell changes.Semantic proximity Read ↗

v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions.Semantic proximity Read ↗

In vivo tumorigenicity and in vitro sensitivity to tumor-necrosis-factor alpha mediated killing of c-Ha-ras-transformed cells.Semantic proximity Read ↗

Two discrete types of tumor necrosis factor-resistant cells derived from the same cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.