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Article

Novel revertants of H-ras oncogene-transformed R6-PKC3 cells.

Molecular and cellular biology - 1 Jul 1992

Krauss R S, Guadagno S N, Weinstein I B

Abstract excerpt

Rat 6 fibroblasts that overproduce protein kinase C beta 1 (R6-PKC3 cells) are hypersensitive to complete transformation by the T24 H-ras oncogene; yet T24 H-ras-transformed R6-PKC3 cells are killed when exposed to 12-O-tetradecanoylphorbol-13-acetate (TPA) (W.-L. W. Hsiao, G. M. Housey, M. D. Jo...

Topics

Animals
Cell Transformation, Neoplastic
Cells, Cultured
Enzyme Activation
Gene Expression Regulation, Neoplastic
Genes, Dominant
Genes, ras
Morphogenesis
Mutagenesis
Oncogene Proteins
Phenotype
Protein Kinase C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-jun

Rats

Source

Open in PubMed Open full text

Identifiers

PMID: 1535685
DOI: 10.1128/mcb.12.7.3117-3129.1992
PMCID: PMC364526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1535685-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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