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Article

Cell transforming genes and tumor progression: in vivo unified secondary phenotypic cell changes.

International journal of cancer - 19 Jan 1998

Deichman G J, Matveeva V A, Kashkina L M, Dyakova N A, Uvarova E N, Nikiforov M A, Gudkov A V

Abstract excerpt

We have earlier shown that Syrian hamster cells spontaneously transformed in vitro during in vivo progression, acquire in 1 step, along with highly increased tumorigenicity, 2 new properties characterizing the [H2O2CA + tPGE(S)] phenotype, i.e., a high H2O2 catabolizing (antioxidant) activity and the ability to release PGE2 upon contact with NK cells. In contrast, RSV-SR-(v-src)-transformed cells acquire the...

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Identifiers

PMID: 9462719
DOI: 10.1002/(sici)1097-0215(19980119)75:2<277::aid-ijc17>3.0.co;2-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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