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Article

v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions.

Experimental cell research - 1 Aug 1997

Meijne A M, Ruuls-Van Stalle L, Feltkamp C A, McCarthy J B, Roos E

Abstract excerpt

The mechanism of v-src-induced morphological transformation is still obscure. We compared LA29 rat fibroblasts, which express a temperature-sensitive (ts) v-src mutant, with D1025 rat fibroblasts, transfected with a ts mutant of v-fps. Upon transformation, LA29 cells adopted an elongated shape with reduced focal adhesions and loss of actin stress fibers. In contrast, activation of v-fps in D1025 cells had little...

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Source

Identifiers

PMID: 9260918
DOI: 10.1006/excr.1997.3637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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