Article
Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22.
American journal of medical genetics - 31 May 1997
Edenberg H J, Foroud T, Conneally P M, Sorbel J J, Carr K, Crose C, Willig C, Zhao J, Miller M, Bowman E, Mayeda A, Rau N L, Smiley C, Rice J P, Goate A, Reich T, Stine O C, McMahon F, DePaulo J R, Meyers D, Detera-Wadleigh S D, Goldin L R, Gershon E S, Blehar M C, Nurnberger J I
Abstract excerpt
As part of the four-center NIMH Genetics Initiative on Bipolar Disorder we carried out a genomic scan of chromosomes 3, 5, 15, 16,17, and 22. Genotyping was performed on a set of 540 DNAs from 97 families, enriched for affected relative pairs and parents where available. We report here the results of the initial 74 markers that have been typed on this set of DNAs. The average distance between markers (theta) was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.