Article
Strategies to identify genes for complex disorders: a focus on bipolar disorder and chromosome 16p.
Psychiatric genetics - 1 Aug 2011
Byerley William, Badner Judith A
Abstract excerpt
Bipolar disorder, also termed manic-depression, is a genetically based neuropsychiatric disorder with heritability estimates of 80%. Over 25 genome-wide linkage studies have been completed for bipolar disorder and results are not all randomly distributed but appear to converge on several chromosomal regions. Recently, several genome-wide association studies have been reported using thousands of cases and controls...
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