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Article

Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20.

Psychiatric genetics - 1 Aug 2008

Ross Jessica, Berrettini Wade, Coryell William, Gershon Elliot S, Badner Judith A, Kelsoe John R, McInnis Melvin G, McMahon Francis J, Murphy Dennis L, Nurnberger John I, Foroud Tatiana, Rice John P, Scheftner William B, Zandi Peter, Edenberg Howard, Byerley William

Abstract excerpt

OBJECTIVE: Our aim is to map chromosomal regions that harbor loci that increase susceptibility to bipolar disorder. METHODS: We analyzed 644 bipolar families ascertained by the National Institute of Mental Health Human Genetics Initiative for bipolar disorder. The families have been genotyped with microsatellite loci spaced every approximately 10 cM or less across the genome. Earlier analyses of these pedigrees...

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Identifiers

PMID: 18628681
DOI: 10.1097/YPG.0b013e3283050aa5
PMCID: PMC4418612

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