Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26.

Molecular psychiatry - 1 May 2009

McAuley E Z, Blair I P, Liu Z, Fullerton J M, Scimone A, Van Herten M, Evans M R, Kirkby K C, Donald J A, Mitchell P B, Schofield P R

Abstract excerpt

Bipolar affective disorder is a heritable, relatively common, severe mood disorder with lifetime prevalence up to 4%. We report the results of a genome-wide linkage analysis conducted on a cohort of 35 Australian bipolar disorder families which identified evidence of significant linkage on chromosome 15q25-26 and suggestive evidence of linkage on chromosomes 4q, 6q and 13q. Subsequent fine-mapping of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Australia
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Chromosomes, Human, Pair 15

Share to DNA Mutational Analysis

Share to Genetic Linkage

Share to Genome-Wide Association Study

Share to Lod Score

Source

Identifiers

PMID: 18227837
DOI: 10.1038/sj.mp.4002146

Genes

NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26.PMID 18227837Read ↗

A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q.Semantic proximity Read ↗

Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes.Semantic proximity Read ↗

A susceptibility locus for bipolar affective disorder on chromosome 4q35.Semantic proximity Read ↗

Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish.Semantic proximity Read ↗

Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12.Semantic proximity Read ↗

Strategies to identify genes for complex disorders: a focus on bipolar disorder and chromosome 16p.Semantic proximity Read ↗

A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26.Semantic proximity Read ↗

A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.Semantic proximity Read ↗

Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.