Article
Scanning the genome with 1772 microsatellite markers in search of a bipolar disorder susceptibility gene.
Molecular psychiatry - 1 Nov 1996
Polymeropoulos M H, Schaffer A A
Abstract excerpt
Bipolar disorder affects approximately 1% of the population and there is evidence that genetic factors play an important role in the production of symptoms. We undertook a genetic linkage study for the discovery of a major locus conferring susceptibility for bipolar illness in an Old Order Amish pedigree. Our study took advantage of publicly available phenotypic and genotypic information, the latter as a...
Topics
- Bipolar Disorder
- Christianity
- DNA, Satellite
- Ethnicity
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Testing
- Genotype
- Humans
- Lod Score
- Male