Article
Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12.
Molecular psychiatry - 1 Mar 2003
Liu J, Juo S H, Dewan A, Grunn A, Tong X, Brito M, Park N, Loth J E, Kanyas K, Lerer B, Endicott J, Penchaszadeh G, Knowles J A, Ott J, Gilliam T C, Baron M
Abstract excerpt
Bipolar disorder (BP) is a severe and common psychiatric disorder characterized by extreme mood swings. Family, twin and adoption studies strongly support a genetic component. The mode of inheritance is complex and likely involves multiple, as yet unidentified genes. To identify susceptibility loci, we conducted a genome-wide scan with 343 microsatellite markers in one of the largest, well-characterized pedigree...
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