Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder.

Human molecular genetics - 1 Aug 2003

Ekholm Jenny M, Kieseppä Tuula, Hiekkalinna Tero, Partonen Timo, Paunio Tiina, Perola Markus, Ekelund Jesper, Lönnqvist Jouko, Pekkarinen-Ijäs Petra, Peltonen Leena

Abstract excerpt

We performed a genome-wide scan for susceptibility loci in bipolar disorder in a study sample colleted from the isolated Finnish population, consisting of 41 families with at least two affected siblings. We identified one distinct locus on 16p12 providing significant evidence for linkage in two-point analysis (Z(max)=3.4). Furthermore, three loci with a two-point LOD score >2.0 were observed with markers on 4q32,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 4

Share to Finland

Share to Genome, Human

Share to Lod Score

Share to Microsatellite Repeats

Share to Monte Carlo Method

Source

Identifiers

PMID: 12874110
DOI: 10.1093/hmg/ddg199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder.PMID 12874110Read ↗

A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2.Semantic proximity Read ↗

Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12.Semantic proximity Read ↗

Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20.Semantic proximity Read ↗

Genome-wide scan of bipolar disorder and investigation of population stratification effects on linkage: support for susceptibility loci at 4q21, 7q36, 9p21, 12q24, 14q24, and 16p13.Semantic proximity Read ↗

Bipolar disorder susceptibility region on Xq24-q27.1 in Finnish families.Semantic proximity Read ↗

A genome-wide linkage search for bipolar disorder susceptibility loci in a large and complex pedigree from the eastern part of Cuba.Semantic proximity Read ↗

Scanning the genome with 1772 microsatellite markers in search of a bipolar disorder susceptibility gene.Semantic proximity Read ↗

Strategies to identify genes for complex disorders: a focus on bipolar disorder and chromosome 16p.Semantic proximity Read ↗

Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees.Semantic proximity Read ↗

A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42.Semantic proximity Read ↗

Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.Semantic proximity Read ↗

SNP fine mapping of chromosome 8q24 in bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.