Article
The dual role of Apl in prophage induction of coliphage 186.
Molecular microbiology - 1 Feb 1997
Reed M R, Shearwin K E, Pell L M, Egan J B
Abstract excerpt
In the present study we show that the Apl protein of the temperate coliphage 186 combines, in one protein, the activities of the coliphage lambda proteins Cro and Xis. We have shown previously that Apl represses both the lysogenic promoter, pL, and the major lytic promoter, pR, and is required for excision of the prophage. Apl binds at two locations on the phage chromosome, i.e. between pR and pL and at the...
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